Dexamethasone oxetanone|CAS 4089-36-5|DC Chemicals

Cas No.:	4089-36-5
Chemical Name:	Dexamethasone oxetanone
SMILES:	C[C@@]12[C@@]3(C(CO3)=O)[C@@H](C[C@@]1([H])[C@@]4([H])[C@]([C@H](C2)O)([C@@]5(C(CC4)=CC(C=C5)=O)C)F)C
Formula:	C₂₂H₂₇FO₄
M.Wt:	374.45
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC45892	Promegestone	Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research.
DC9605	Dienogest	Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.
DC77029	Onapristone	Onapristone is a progesterone receptor antagonist, with Kds of 11.6 nM and 11.90 nM for human endometrium and myometrium progesterone receptor in saturation analysis. Onapristone has antitumor activity.
DC77028	11α-Hydroxytestosterone	11α-Hydroxytestosterone is a deriviative of Hydrocortisone, with the relative binding affinity to progesterone receptor of 9% (comparing to R5020119384) 100%). 11α-Hydroxytestosterone inhibits the growth and differentiation of human decidual cells in culture.
DC73853	AG-205	A small molecule inhibitor of progesterone receptor membrane component 1 (PGRMC1) that alters the spectroscopic properties of the PGRMC1-heme complex.
DC72233	Norgestrienone	Norgestrienone, progestin or synthetic progestin, is a progestin receptor agonist. Norgestrienone is often used as a progestational compound in birth control pills and can be used in combination with ethinyl estradiol.
DC71566	Dexamethasone oxetanone	Dexamethasone oxetanone (Dex-Ox), a derivative of the glucocorticoid-selective steroid Dexamethasone (Dex), is an antiglucocorticoid. Dexamethasone oxetanone is an antiprogestin with significant agonist activity with progesterone receptor (PR) A and B isoforms.
DC49828	Progesterone-13C2	Progesterone-13C2 (Pregn-4-ene-3,20-dione-13C2) is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.