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EM12-FS

  Cat. No.:  DC67406   Featured
Chemical Structure
2839138-44-0
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More than 5000 active chemicals with high quality for research!
Field of application
EM12-FS is a bifunctional CRBN modulator that engages cereblon at His353 while functioning as a molecular glue to induce NTAQ1 degradation. Demonstrating favorable pharmacokinetics, it exhibits a human plasma half-life of 196 minutes, supporting its therapeutic potential.
Cas No.: 2839138-44-0
Chemical Name: 2-(2,6-dioxopiperidin-3-yl)-3-oxo-2,3-dihydro-1H-isoindol-5-yl sulfurofluoridate
Synonyms: Z6569837298;2-(2,6-dioxopiperidin-3-yl)-3-oxo-2,3-dihydro-1H-isoindol-5-yl sulfurofluoridate
SMILES: S(=O)(=O)(OC1C=CC2=C(C=1)C(N(C2)C1C(NC(CC1)=O)=O)=O)F
Formula: C13H11FN2O6S
M.Wt: 342.299645662308
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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