O4I4|CAS 412008-21-0|DC Chemicals

Cas No.:	412008-21-0
Chemical Name:	2-Thiazolamine, 4-(1,1-dimethylethyl)-N-(2,3-dimethylphenyl)-
Synonyms:	2-Thiazolamine, 4-(1,1-dimethylethyl)-N-(2,3-dimethylphenyl)-;412008-21-0;4-tert-butyl-N-(2,3-dimethylphenyl)thiazol-2-amine;O4I4;BDBM50183098;CS-0881067;HY-155528;SCHEMBL14433276;CHEMBL206789;OCT4-inducing compound 4;DA-66292
SMILES:	S1C(NC2C=CC=C(C)C=2C)=NC(=C1)C(C)(C)C
Formula:	C₁₅H₂₀N₂S
M.Wt:	260.397702217102
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
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DC75816	Nisoxetine	Nisoxetine acts as a highly selective and potent noradrenaline transporter (NET) antagonist, exhibiting a binding affinity (Kd) of 0.76 nM. In addition to its antidepressant properties, nisoxetine functions as a local anesthetic by inhibiting voltage-gated sodium channels. This dual pharmacological activity makes it a compound of interest for both neurological and pain management research.
DC75641	GENZ-644282 TFA salt	Genz-644282, also known as SAR402674, is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.
DC75325	PSMA-617 TFA	PSMA-617, also know as vipivotide tetraxetan, is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA617 possesses a small peptide, which was designed to target prostate-specific membrane antigen (PSMA). PSMA617 demonstrates high radiolytic stability for at least 72 h. PSMA617 has high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined). 177 Lu-PSMA-617 offers a potential additional life-prolonging treatment option for men with mCRPC.
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DC74748	O4I4	O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability.
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