PPACK II diTFA|CAS 649748-23-2|DC Chemicals

Cas No.:	649748-23-2
Chemical Name:	PPACK II diTFA
SMILES:	O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O
Formula:	C₂₉H₃₅ClF₆N₆O₇
M.Wt:	729.07
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC76983	RWJ-58643 hydrochloride	RWJ-58643 hydrochloride is a β-trypsin inhibitor that inhibits allergic inflammation. RWJ-58643 hydrochloride (1 g) significantly reduces nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 hydrochloride causes late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 hydrochloride modulates allergic reactions by inhibiting the release of β-trypsin from mast cells.
DC76982	L-Isoleucyl-L-valine	L-Isoleucyl-L-valine (Ile-Val) is a dipeptide that induces the bovine trypsinogen-trypsin transition.
DC76981	Benzamidine	Benzamidine is a reversible competitive trypsin inhibitor with a Ki of 19 μM. Benzamidine shows inhibitory activity against homogeneous boar sperm acrosin with a Ki of 4 μM.
DC72681	SPC4061	SPC4061 an antisense nucleotide, is a potent PCSK9 inhibitor. SPC4061 targets the lock-in nucleic acid (LNA) of PCSK9 for the study of hypercholesterolemia and related diseases.
DC72680	PPACK II diTFA	PPACK II diTFA is an irreversible and specific glandular and plasma kallikreins inhibitor.
DC72409	AAF-CMK	AAF-CMK is a TPPII (tripeptidylpeptidase II) inhibitor, shows anti-tumor activity and induces apoptosis. AAF-CMK can be used in leukemia research.
DC72231	Cyclotheonamide A	Cyclotheonamide A is a serine protease inhibitor (cyclic polypeptide), which can be obtained from marine sponges of the genus Theonella. Cyclotheonamide A shows potent inhibitory activity against trypsin (Ki=0.023 µM) and streptokinase (Ki=0.035 µM) and moderate inhibitory activity against human α-thrombin (Ki=0.18 µM). Cyclotheonamide A can be used in study of antithrombotic.
DC72230	UAMC-00050	UAMC-00050 is a potent trypsin-like serine protease inhibitor. UAMC-00050 can be used in research of dry eye syndrome and ocular inflammation.
DC71824	Tilpisertib fosmecarbil	Tilpisertib fosmecarbil is a potent serine/threonine kinase inhibitor. Tilpisertib fosmecarbil has anti-inflammatory activity.
DC71823	Bezeparsen	Bezeparsen is a PCSK9 synthesis inhibitor.