PROTAC KRAS G12C degrader-1|CAS |DC Chemicals

Cas No.:
Chemical Name:	PROTAC KRAS G12C degrader-1
SMILES:	OC1=CC2=C(C(C3=C(C4=C(C=C3Cl)C(N5CCN(CC5)C(C=C)=O)=NC(NCCCCCCCCCCCCNC6=C(C7=CC=C6)C(N(C7=O)C8CCC(NC8=O)=O)=O)=N4)F)=C1)C=CC=C2
Formula:	C₅₀H₅₄ClFN₈O₆
M.Wt:	917.47
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC47585	PROTAC CDK9 ligand-1	PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs.
DC47584	PROTAC BRD4 ligand-2	PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718.
DC47372	Bromo-C10-OBn	Bromo-C10-OBn is a PROTAC linker that can be used in the synthesis of PROTACs.
DC47371	1-Bromo-6-chlorohexane	1-Bromo-6-chlorohexane is a PROTAC linker can be used in the synthesis of PROTACs.
DC47370	Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)	Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
DC47369	Propargyl-PEG2-CH2COOH	Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
DC47319	Dovitinib-RIBOTAC	Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.
DC47213	L-Homopropargylglycine hydrochloride	L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor.
DC47212	Boc-bipiperidine-ethynylbenzoic acid	Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61.
DC47193	OICR-9429-N-C2-NH2	OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs.