(Rac)-Fidarestat|CAS 105300-43-4|DC Chemicals

Cas No.:	105300-43-4
Chemical Name:	(Rac)-Fidarestat
SMILES:	O=C(N1)C2(NC1=O)C3=C(C=CC(F)=C3)OC(C(N)=O)C2
Formula:	C₁₂H₁₀FN₃O₄
M.Wt:	279.22
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC76824	WF-3681	WF-3681 (compound 1) is an aldose reductase inhibitor and a fungal metabolite.
DC76823	RJG-2051	RJG-2051 is a selective covalent aldo-keto reductase family 1 member C3 (AKR1C3) inhibitor with an IC50 value of 13 nM. RJG-2051 interferes with the metabolic process of substrates such as androgens, estrogens, and prostaglandins by AKR1C3. RJG-2051 is promising for research of cancers.
DC76822	M79175	M79175 is an aldose reductase inhibitor that can be used in the study of early diabetic retinopathy.
DC76821	(Rac)-Fidarestat	(Rac)-Fidarestat ((Rac)-SNK 860) is the racemate of Fidarestat-resistant hepatitis B.
DC73712	Imirestat	Imirestat (AL-1576) is a potent aldose reductase inhibitor with IC50 of 8.5 nM for rat lens aldose reductase, with similar IC50 value for the human placental enzyme, shows high affinity for AKR1A1 and AKR1B1 with Ki of 47 and 46 nM respectively.
DC73711	BAY1128688	BAY1128688 is a potent, steroidal aldo-keto reductase 1C3 (AKR1C3) inhibitor with potential for endometriosis.
DC49723	Aldose reductase-IN-2	Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR). Aldose reductase-IN-2 has antioxidation capacity. Aldose reductase-IN-2 is a promising anti-diabetic complications agent.
DC49722	Aldose reductase-IN-3	Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 μM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis.