TP-1454|CAS 2490276-04-3|DC Chemicals

Cas No.:	2490276-04-3
Chemical Name:	1H-Pyrazole-5-carboxamide, N-[(2-amino-6-fluorophenyl)methyl]-N-[2-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)ethyl]-3-(trifluoromethyl)-
Synonyms:	1H-Pyrazole-5-carboxamide, N-[(2-amino-6-fluorophenyl)methyl]-N-[2-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)ethyl]-3-(trifluoromethyl)-
SMILES:	N1C(C(N(CC2=C(F)C=CC=C2N)CCC2CCS(=O)(=O)CC2)=O)=CC(C(F)(F)F)=N1
Formula:	C₁₉H₂₂F₄N₄O₃S
M.Wt:	462.46
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

TP-1454 is an activator of PKM2 with AC50 of 10 Nm in biochemical assays.TP-1454 modulates tumor-immune responses by destabilizing T-regulatory cells.

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