Itareparib is the inhibitor for PARP and exhibits antineoplastic activity.

EAPB0503 is a quinoline compound with anti-tumor activity, showing strong cytotoxicity against melanoma cells in vitro (IC50=200 nM). EAPB0503 can induce specific cell cycle arrest in mitosis of CML cells and directly activate apoptosis, leading to an increase in the G0 cell population, disruption of mitochondrial membrane potential, PARP cleavage, and DNA fragmentation. EAPB0503 also reduces the levels of BCR-ABL protein .

BSI-401 is an orally active PARP-1 inhibitor. BSI-401 alone and in synergism with Oxaliplatin. Ocifisertib hydrochloride is an orally active PLK4 inhibitor with a Ki and an IC50 of 0.26 nM and 2.8 nM. Ocifisertib hydrochloride inhibits growth of various cancer cells, arrests cell cycles at G2/M phase, and induces apoptosis. Ocifisertib hydrochloride exhibits antitumor efficacy in mouse model.

Benadrostin is a Poly(ADP-ribose) synthetase inhibitor with an IC50 of 35 μM.

ARCher-142 (compound S8) is a potent tankyrase inhibitor. ARCher-142 selectively binds to ARC4 with potency of 8 µM.

(rac)-Talazoparib ((rac)-BMN-673) (Compound 47) is the orally active inhibitor for PARP1/2 with Ki of 1.2 nM and 0.87 nM. (rac)-Talazoparib inhibits cellular PARylation with an EC50 of 2.51 nM. (rac)-Talazoparib causes the accumulation of DNA damage, inhibits proliferation of BRCA1/2-mutated MX-1 cell and Capan-1 cell with IC50 of 0.3 nM and 5 nM. (rac)-Talazoparib exhibits antitumor efficacy in mouse models.

UnyLinker 12 TEA is a universal linker that can be used to synthesize oligoribonucleotides.

Ribavirin 5'-monophosphate dilithium is an active form of ribavirin that inhibits IMP dehydrogenase, and ribavirin itself is a broad-spectrum antiviral agent.

Pseudouridine 5'-OTBDPS (5-(5-O-TBDPS-β-D-ribofuranosyl)uracil) is an intermediate of Pseudouridine. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.

N-Acetyl-2', 3'-Acetyl-Guanosine is a modified guanosine nucleoside.

LNA-UTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

LNA-GTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

LNA-GDP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

LNA-CTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

LNA-ATP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

LNA-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

Isoorotidine is a nucleoside derivative and an isomer of the pyrimidine nucleoside Orotidine, is human erythrocyte acetylcholinesterase (AChE) inhibitor.

DL-Alanosine is an amino acid analogue with antitumor activities.

AA-UTP tetrasodium is an amine-modified nucleotide that can be directly incorporated into labeled-UTP. DG013B has weak affinity for ERAP1 and ERAP2 and is often used as a negative control to study the binding properties of DG013A and its analogues to ERAP1 and ERAP2.

8-Nitro-2'3'cAMP is composed of 8-nitro-AMP, ribose and phosphate, and is a cyclic nucleotide derivative.

7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a building block of nucleic acid.

5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli.

3'-Deoxy-3'-amino-ATP tetrasodium is an ATP substitute created by inserting an amino acid at the C3 position of ATP. 3'-Deoxy-3'-amino-ATP tetrasodium catalyzes RNA synthesis in the presence of RNA polymerase.

3'-Amino-3'-dGTP tetrasodium is a substitute for GTP, produced by inserting an amino acid into the C3 position of GTP.

2'-O-MOE-UTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2'-O-MOE-GTP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2'-F-UMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2'-F-CMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2'-F-CDP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2'-F-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.