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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC28589 | CMLD012072 |
CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity.
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| DC28588 | CMLD012612 |
CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC50 value of 2 nM. CMLD012612 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A) and possesses potent anti-neoplastic activity.
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| DC12317 | A-484954 |
A-484954 is a highly selective eukaryotic elongationfactor-2 (eEF2) inhibitor, with an IC50 of 280 nM.
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| DC11621 | eIF4A3-IN-1q |
A potent, subtype-selective, orally available eIF4A3 inhibitor with IC50 of 0.14 uM.
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