The calcium salt of levomefolic acid that has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. .

The antiglucocorticoid RU43044 exerted significant agonist activity and activated MMTV-Luc transcription in osteosarcoma cells but not human breast cancer cells.

The (1R,2R) diastereomer of 2-PCCA, a potent, selective agonist of the orphan GPR88 receptor with EC50 of 373 nM, 5-fold more potent than the (1S, 2S)-isomer..

Thapsigargin is an inhibitor of microsomal Ca2+-ATPase.

TH 5427 (TH5427) is a potent, small molecule NUDT5 (NUDIX5) inhibitor with IC50 of 29 nM, 690-fold selectivity for NUDT5 over MTH1 (NUDT1) in vitro.

TGR-1202 R-enantiomer is is the less active enantiomer of TGR-1202 (Umbralisib), TGR-1202 is a potent, selective, orally available PI3Kδ inhibitor with IC50 of 22 nM..

Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor.

Tetrodotoxin (TTx) is a potent, highly selective sodium channel blocker with IC50 of 33 nM for Nav1.6.

Tetramisole hydrochloride is an inhibitor of alkaline phosphatases, is a high purity antiparasitic.

Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry.

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release.

Tesmilifene is a novel agent that augments cytotoxicity of various chemotherapeutic agents both in vitro and in vivo. It binds selectively to the high-affinity microsomal antiestrogen binding site (Ki=50nm) but has no affinity for estrogen receptors. Inhi

TES-991 is a potent and selective human α‑Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) inhibitor, with an IC50 of 3 nM.

tert-butyl 2-cyano-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate..

Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.

Terbutryn is a selective herbicide and a triazine compound. It is absorbed by the roots and foliage and acts as an inhibitor of photosynthesis.

Tenofovir(GS 1278, PMPA) is an antiretroviral drug known as nucleotide analogue reverse transcriptase inhibitors (NRTIs), which block reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV.

Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM. IC50 value: 1 nM [1] Target: DPP4 in vi

Tenapanor (AZD-1722;RDX5791) is a potent, selective inhibitor of the Na+/H+ exchanger 3 (NHE3) with IC50 of 5 and 10 nM for human and rat NHE3, respectively.

Tenalisib (RP6530) is a novel, potent, and selective PI3Kδ and PI3Kγ inhibitor with IC50 values of 25 and 33 nM, respectively.

Temocapril Hydrochloride is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

Telotristat (LP-778902) is a potent, small-molecule inhibitor of peripheral serotonin synthesis, acts by inhibiting tryptophan hydroxylase (TPH) with IC50 of 28 nM, demonstrates potential for the treatment of carcinoid syndrome..

Telbivudine (Tyzeka, Sebivo) is an antiviral agent used in the treatment of hepatitis B infection.

Tedizolid is the active moiety of the prodrug tedizolid phosphate, with high potency against Gram-positive species.

Tecalcet (R-568.

Tecalcet (R-568.

Tebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM.

TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction (IC50=1.67 uM) but also retains potency toward the Aβ42 aggregation inhibition process.

TD-6450 is a next generation, potent HCV NS5A inhibitor that has potent antiviral activity against HCV infection..

TCN238 is a positive allosteric mGlu4 receptor modulator with an EC50 of 1 μM.