Novel Dual p38α MAPK/PDE-4 Inhibitor with Activity against TNFα -related Diseases

Novel KDM4 inhibitor, inhibiting equally all members of the KDM4 family and exhibiting modest selectivity over other JmjC-KDMs including KDM2A and PHF8

Novel selective inhibitor of KDM4s, inhibiting all members of the KDM4(A-E) subfamily

Novel inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation

Novel cell-permeable, potent, reversible, and substrate competitive LSD1 inhibitor, promoting the adipogenic differentiation of hESCs

The first clickable, photoreactive probe that inhibits both γ-secretase and PSase activities and specifically labels PS1-NTF and signal peptide peptidase (SPP)

Novel Protein kinase A and B inhibitor

Novel inhibitor of Mycobacterium marinum MelF (Rv1936), exhibiting bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro

Novel potent inhibitor of filamentation and biofilm formation by the Candida albicans SC5314 strain

Novel inhibitor of HIV-1 gene expression

Selective inhibitor of Adenylyl Cyclase isoform-2 (AC2)

Novel inhibitor of Mycobacterium marinum MelF (Rv1936), exhibiting bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro

Novel inhibitor of HIV-1 entry

Selective sphingosine kinase 1 (SK1) inhibitor

Novel inhibitor of Mycobacterium marinum MelF (Rv1936), exhibiting bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro

Dual thymidylate synthase and dihydrofolate reductase inhibitor

Novel Cell_cycle>cell cycle inhibitor

Novel IκB kinase inhibitor

Novel Cyclin-dependent kinase inhibitor

Novel Thymidine kinase (TK) inhibitor

Novel IκB kinase inhibitor

Novel SRC kinase inhibitor

Novel RAF kinase inhibitor

Novel Mdm2 inhibitor, an analog of Nutlin-3

Novel Mdm2 inhibitor, an analog of Nutlin-3

Novel potent CysLT2 receptor antagonist

Isoform-selective inhibitor of histone deacetylase (HDAC1)

Selective inhibitor of 15-hydroxy PGDH, significantly suppressing endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE

Novel ligand of voltage-gated calcium channel α2δ-1 subunit (Cavα2δ-1)

Novel selective reversible inhibitor of cathepsin X