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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC34987 1-(t-Boc-Aminooxy)-3-aminooxy-propane
1-(t-Boc-Aminooxy)-3-aminooxy-propane is an Aminooxy PEG Linker. Aminooxy-PEG can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage.
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DC34981 Aminooxy-PEG7-methane
Aminooxy-PEG7-methane is a PEG derivative containing an aminooxy group and a methane group. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. PEG Linkers may be useful in the development of antibody drug conjugates or drug delivery methods.
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DC34932 m-PEG10-amine
m-PEG10-amine is a PEG derivative containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34930 Amino-PEG8-t-Boc-hydrazide
Amino-PEG8-t-Boc-hydrazide is a PEG derivative containing an amino group and a Boc-protected hydrazide. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34919 Azido-PEG3-amine
Azido-PEG3-amine is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34888 Amino-PEG3-CH2CO2H
Amino-PEG3-CH2CO2H is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34887 Amino-PEG2-CH2CO2H
Amino-PEG2-CH2CO2H is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34828 Propargyl-PEG4-thiol
Propargyl-PEG4-thiol is a crosslinker containing a propargyl group and thiol group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
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DC34821 Bis-propargyl-PEG13
Bis-propargyl-PEG13 is a PEG derivative containing two propargyl groups. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers are useful in the development of antibody drug conjugates.
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DC34820 Bis-propargyl-PEG10
Bis-propargyl-PEG10 is a PEG derivative containing two propargyl groups. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers are useful in the development of antibody drug conjugates.
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DC34818 Bis-propargyl-PEG8
Bis-propargyl-PEG8 is a PEG derivative containing two propargyl groups. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC34789 Propargyl-PEG6-t-butyl ester
Propargyl-PEG6-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC34788 Propargyl-PEG4-t-butyl ester
Propargyl-PEG4-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC34787 Propargyl-PEG3-t-butyl ester
Propargyl-PEG3-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC34729 Aminacrine HCl
Aminacrine hydrochloride is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.
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DC34728 Amiben DS
Chloramben is a selective herbicide used to control the seedlings of broadleaf weeds and annual grasses. It is mostly used for soybeans, but also for dry beans, peanuts, sunflowers, peppers, cotton, sweet potatoes, squash, hardwood trees, shrubs, and some conifers.
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DC34683 Aacaptan
Captan is a non-systemic fungicide used to control diseases of many fruit, ornamental, and vegetable crops.
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DC34600 NOR3
FK409 is a cell permeable NO donor which produces vasorelaxation.
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DC34586 AG538
AG-538 is a PI5P4Kα inhibitor which targets the ATP site.
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DC34561 Bisindolylmaleimide VII
Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.
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DC34524 Ascorbate
Ascorbate, also known as Ascorbicin, is a DNase I inhibitor. Ascorbate is an antioxidant which functions as a reducing agent and coenzyme in several metabolic pathways.
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DC34503 Marfanil
Mafenide Hydrochloride is an antibiotic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa.
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DC34501 (E)-Metominostrobin
Metominostrobin is a broad-spectrum fungicide.
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DC34471 GA3-AM
GA3-AM is a cell permeable chemical dimerizer.
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DC34450 Fendiline Hydrochloride
Fendiline HCl is a potent acid sphingomyelinase (ASM) inhibitor, reducing the phosphatidylserine (PtdSer) and cholesterol content of the inner plasma membrane and inhibiting calcium function in muscle cells in excitation-contraction coupling.
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DC34448 UK-78282 Hydrochloride
UK-78282 HCl is a blocker of the KV1.3 and KV1.4 voltage-gated potassium channels.
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DC34399 R(+)-6-Bromo-APB hydrobromide
R(+)-6-Bromo-APB HBr is a potent D1 Dopamine receptor agonist.
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DC34386 RTC13
RTC13 is a premature termination codon (PTC) readthrough inducer that acts by restoring dystrophin expression and improving muscle function in the mdx mouse model for Duchenne muscular dystrophy.
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DC34278 OG-L002 HCl
OG-L002 HCl is an inhibitor of LSD1.
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DC34268 PK-THPP
PK-THPP is a TASK-3 channel blocker.
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