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Cat. No. Product Name Field of Application Chemical Structure
DC36291 NAP-1
NAP-1 is a compound with anesthetic activity. It increases paired-pulse inhibition in the CA1 region of the hippocampus.
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DC36259 7,8-Dihydroneopterin
7,8-Dihydroneopterin is a pteridine with antioxidant activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and inhibits copper ion-induced oxidation of LDL. It also decreases thiobarbituric acid reactive substances (TBARS) produced by THP-1 cells cultured with LDL, and it inhibits necrosis induced by oxidized LDL (oxLDL).
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DC36255 N-desmethyl Ivabradine (hydrochloride)
N-desmethyl Ivabradine (hydrochloride) is an active metabolite of ivabradine. Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4.
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DC36216 Amizole
Sulfamidopyrine sodium is an impurity of Dipyrone --- a non-steroidal anti-inflammatory drug NSAID) that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance.
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DC36213 Amistar
Azoxystrobin is a strobilurin fungicide that inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1.
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DC36194 AM-211 sodium
AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it shows selectivity over other prostanoid receptors and enzymes. AM211 exhibits good oral bioavailability in rats and dogs and dose-dependently inhibits 13,14-dihydro-15-keto-PGD(2)-induced leukocytosis in a guinea pig pharmacodynamic assay.
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DC36186 ALP 201
SUN-5555 is a penem --- a type of unsaturated β-lactam with a sulfur atom in the five-membered ring. SUN-5555 belongs to the penem group of antibiotics prescribed for oral usage. Enterobacteriaceae bacterial infections with cephalosporin resistance are susceptible to faropenem. Faropenem could be an effective antibiotic to treat urinary tract infections caused by extended-spectrum beta-lactamases (ESBL) producing bacteria.
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DC36178 Alios
Triticonazole is a fungicide.
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DC36131 FP-846
Sulfentrazone, also known as FP-846, is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.
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DC36104 (+)-Razoxane hydrochloride
Dexrazoxane hydrochloride is a cardioprotectant. Studies have shown that usage of this drug before anthracycline chemotherapy in pediatric patients with AML may improve cardiac function indices such as ejection fraction and shortening fraction. Adding dexrazoxane to doxorubicin in adjuvant therapy patients may lead to higher rates of bone marrow suppression, more febrile neutropenia events, and dose reductions.
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DC36075 A-hydroCort
Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.
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DC36074 AR-C133913XX
Ticagrelor metabolite M5, also known as AR-C133913XX, is a metabolite of Ticagrelor which is the first reversible oral P2Y12 receptor antagonist. Ticagrelor provides faster and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
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DC36066 AQ-RA 741
AQ-RA 741 is a tricyclic antimuscarinic drug.
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DC36012 Lipoamide-PEG3-Mal
Lipoamide-PEG3-Mal is a PEG Linker.
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DC36007 Lipoamido-PEG4-acid
Lipoamido-PEG4-acid is a PEG Linker.
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DC35961 Ms-PEG2-t-butyl ester
Ms-PEG2-t-butyl ester is a PEG Linker.
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DC35955 Tos-PEG4-methyl ester
Tos-PEG4-methyl ester is a PEG Linker.
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DC35935 Tos-PEG2-t-butyl ester
Tos-PEG2-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
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DC35900 Bromo-PEG2-phosphonic acid diethyl ester
Bromo-PEG2-phosphonic acid diethyl ester is a PEG Linker.
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DC35889 Bis-PEG4-PFP ester
Bis-PEG4-PFP ester is a PEG Linker.
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DC35888 Bis-PEG3-PFP ester
Bis-PEG3-PFP ester is a PEG Linker.
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DC35847 tert-butyl 6-(2,5-dioxo-2H-pyrrol-1(5H)-yl)hexylcarbamate
tert-butyl 6-(2,5-dioxo-2H-pyrrol-1(5H)-yl)hexylcarbamate contains a maleimide group and a Boc-protected amine group. The protected amine can be deprotected by acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35826 Mal-amido-PEG4-acid
Mal-amido-PEG4-acid is a PEG derivative containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35802 Mal-PEG4-NHS ester
Mal-PEG4-NHS ester is a PEG derivative containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35797 Mal-PEG5-acid
Mal-PEG5-acid is a PEG derivative containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC35782 N-Boc-N-bis(PEG3-azide)
N-Boc-N-bis(PEG3-azide) is a branched PEG derivative with two terminal azide groups and a Boc protected amino group. The azide groups enable PEGylation via Click Chemistry. The protected amine can be deprotected by acidic conditions.
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DC35763 NH-bis(PEG3-azide)
NH-bis(PEG3-azide) is a PEG derivative containing an amino group with two azide groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls. The azide groups enable PEGylation via Click Chemistry.
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DC35759 S-Acetyl-PEG3-azide
S-Acetyl-PEG3-azide is a PEG derivative containing an azide group and a sulfur acetyl group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35751 Azido-PEG3-CH2CO2Me
Azido-PEG3-CH2CO2Me is a crosslinker containing an azide group a methyl ester. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35743 1-isothiocyanato-PEG3-Azide
1-isothiocyanato-PEG3-Azide is a crosslinker containing an azide group and isothiocyanato group. The azide group enables PEGylation via Click Chemistry. Isothiocyanate and its linkage isomer thiocyanate are ligands in coordination chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
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