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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC36927 Immepip (hydrobromide)
Immepip (hydrobromide) is a histamine H3 receptor agonist selective for histamine H3 over H1 and H2 receptors in CHO cell membranes expressing the guinea pig and human receptors.
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DC36920 Sonepiprazole
Sonepiprazole is a a selective dopamine D4 antagonist.
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DC36880 Noratropine
Noratropine is a metabolite of Atropine (A794625).
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DC36835 ARN14686
ARN14686 is an activity-based affinity probe for the detection of N-acylethanolamine acid amidase (NAAA) using click chemistry.
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DC36815 Flonicamid
Flonicamid is a pyridinecarboxamide insecticide. Flonicamid inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi and rats. Formulations containing flonicamid have been used for the control of pest insects in agriculture.
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DC36792 Clemastine
Clemastine is an FDA approved antimuscarinic compound that has been found to rescue impaired myelination and reverse social avoidance behavior in mice.
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DC36747 Benodanil
Benodanil is an agricultural chemical primarily used as a fungicide, bactericide, and wood preservative.
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DC36662 1,10-diiodo-Decane
Decane, 1,10-diiodo- is used as an alkylating agent in the synthesis of symmetrical and unsymmetrical bis-cryptophanes and as a crosslinking reagent for tetrabutylammonium polygalacturonic acid. it is also used to produce decane at temperature of 20°C.
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DC36611 Desbutylbupivacaine
Desbutylbupivacaine also known as N-Desbutyl Bupivacaine, it is a major metabolite of Bupivacaine.
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DC36590 Deacetyl-7-aminocephalosporanic acid
Deacetyl-7-aminocephalosporanic acid is intermediate in the semi-synthetic cephalosporins synthesis. It is found in Acremonium chrysogenum.
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DC36569 NSC 109555
NSC 109555
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DC36562 Lauramine oxide
Lauryldimethylamine oxide (LDAO), also known as dodecyldimethylamine oxide (DDAO), is an amine oxide based nonionic surfactant, with a C12 (dodecyl) alkyl tail. It is one of the most frequently-used surfactants of this type. Like other amine oxide based surfactants it is antimicrobial, being effective against common bacteria such as S. aureus and E. coli, however it is also non-denaturing and may be used to solubilize proteins.
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DC36470 ARN14988
ARN14988 is a potent inhibitor of acid ceramidase that increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells.
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DC36467 CI-898 HCl
CI-898 HCl is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). It has enhanced binding to DHFR in the presence of the cofactor NADPH. Cl-898 HCl inhibits cell growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine (6-TG) in mice with advanced stage P338 leukemia.
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DC36454 Carboxyibuprofen
Ibuprofen carboxylic acid is a major metabolite of ibuprofen.
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DC36450 Terpendole C
Terpendole C is an indole diterpene alkaloid fungal metabolite and inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT). It also inhibits ACAT in J774 macrophages without affecting cell growth.
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DC36424 BODIPY 558/568 C12
BODIPY 558/568 C12 is a fatty acid-conjugated fluorescent probe for lipid droplets. It displays excitation/emission maxima of 558/568 nm, respectively, and has been used to monitor the localization and dynamics of lipid droplets in live cells.
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DC36416 LL-D 37187α
Martinomycin is a polyether antibiotic active against a variety of bacteria including 11 strains of S. aureus, three strains of S. pneumoniae, and E. faecalis.
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DC36394 Collismycin A
Collismycin A is a bacterial metabolite with antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria and fungi. It inhibits proliferation of A549 lung, HCT116 colon, HeLa cervical cancer cells, and NIH373 fibroblasts but not MDA-MD-231 breast cancer cells. Collismycin A forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, and the addition of iron ions inhibits the antiproliferative effect of collismycin A on HeLa cells, an effect that does not occur with the addition of zinc, manganese, copper, or magnesium ions. Collismycin A (1 μM) prevents apoptosis in the brain region of zebrafish larvae by 44% in a model of neuronal cell death induced by all-trans retinoic acid.
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DC36393 RK-682 (rac-1)
TAN 1364B is a protein tyrosine phosphatase (PTP) inhibitor and the racemic and monomeric form of RK-682. TAN 1364B inhibits the activity of the PTPs LMW-PTP, CDC25B, and PTP1B, but the inhibitory activity against LMW-PTP and CDC25B is blocked in the presence of magnesium. TAN 1364B forms aggregates in solution and binds to both the PTP binding site and to protein surfaces.
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DC36392 Deoxyfusapyrone
Deoxyfusapyrone is an α-pyrone fungal metabolite that has antifungal activity. It is active against C. neoformans, A. fumigatus, A. niger, and A. flavus human mycoses. Deoxyfusapyrone is also active against a variety of filamentous fungi, but not yeast or the bacterium B. megaterium.
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DC36340 BMY 29304
Siamycin I is a tricyclic peptide with antiviral and antibacterial activities. It is active against HIV-1 and CBL-20 strain of HIV-2. Siamycin I inhibits HIV-induced fusion of C8166 T cells with HIV-1-infected CEM-SS cells. It is also active against B. subtilis, M. luteus, and S. aureus. Siamycin I inhibits autophosphorylation of the E. faecalis quorum sensing kinase FsrC induced by gelatinase biosynthesis-activating pheromone (GBAP).
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DC36257 Z-LRGG-AMC (trifluoroacetate salt)
Z-LRGG-AMC TFA is a fluorogenic substrate for isopeptidase T. Upon enzymatic cleavage by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify isopeptidase T activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
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DC36256 3-BODIPY-Propanoic Acid
BODIPY 503/512 is a lipophilic, amine-reactive fluorescent probe. It has been used to label oligonucleotide probes and primers for the quantitation of DNA and RNA by PCR and to monitor the uptake and trafficking of BODIPY-labeled proteins and other compounds within cells by fluorescence microscopy. BODIPY 503/512 has also been used to identify and sort adipocytes from mouse white and brown adipose tissue by flow cytometry. It displays excitation/emission maxima of 503/512 nm, respectively.
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DC36234 Aminopyralid
Aminopyralid is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. It is in the picolinic acid family of herbicides, which also includes clopyralid, picloram, triclopyr, and several less common herbicides.
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DC36224 2-Aminofluorene
2-Aminofluorene is a biochemical.
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DC36169 AL-6598
AL-6598 is a DP prostaglandin receptor agonist which may lead to sustained intraocular pressure reduction. This bioactivity may be useful in the treatment of glaucoma.
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DC36138 GT-2016
GT-2016 is an H3 antagonist that may play a role in cognition.
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DC36135 Methimepip dihydrobromide
Methimepip dihydrobromide is a histamine agonist which is highly selective for the H3 subtype. It is the N-methyl derivative of immepip.
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DC36103 Doxycycline monohydrate
Doxycycline monohydrate is a synthetic tetracycline derivative with similar antimicrobial activity.
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