Potent and selective partial agonist of ecdysone receptor (EcR)

Natural phytosterol, showing antidiabetes activities

Antioxidant; Aldose reductase inhibitor

Novel Orally Available Potent Inhibitor against Broad-Spectrum Mutants of c-KIT Kinase for Gastrointestinal Stromal Tumors

Novel Potent Fms-like Tyrosine Kinase 3 Internal Tandem Duplications (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia

Potent and selective FLT3 inhibitor

Novel potent and highly selective irreversible Brutons tyrosine kinase (BTK) inhibitor, inhibiting BTK Y223 auto-phosphorylation

Hydrophilic prodrug of CHM-1

Serotonin transporter substrate

Sympathomimetic agent, facilitating the release of catecholamines, especially noradrenaline and dopamine, from nerve terminals in the brain and also inhibiting their uptake

Widely used biocidal agent

Antiviral and antifungal agent

Novel potent inhibitor of HIV-1 integrase

Novel Potent and Selective Chikungunya Virus Envelope Protein Inhibitor

Potent, long-acting, and selective muscarinic M3 receptor antagonist

Potent, tissue-selective estrogen receptor modulator

Novel acetylcholinesterase inhibitor

Novel dual inhibitor of cholinergic dysfunction and amyloid deposition for AD treatment, penetrating the blood-brain barrier (BBB) and enhancing the cerebral acetylcholine level

Novel potent and orally active ChemR23 inhibitor (IC 80 = 12 nM), showing a long-acting effect in cynomolgus monkeys

Inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase

Novel inhibitor against Lactate Dehydrogenase (LDH) of Cryptosporidium parvum

Novel intracellular chelator, disrupting iron homeostasis in bacteria

Novel potent and selective kynurenine mono-oxygenase (KMO) inhibitor

The desmethyl precursor of CHDI-180R which is a first-in-class high-affinity PET imaging ligand specific for mHTT aggregates

Novel inhibitor of mitochondrial respiration, targeting drug-resistant cancer cells with stem-like features by inhibiting mitochondrial respiration complex I (NADH:ubiquinone oxidoreductase, complex I [CI])

Novel Hsp90 inhibitor

Potent Androgen_receptor>androgen receptor (AR) pure antagonist which did not produce the agonist metabolite

Novel Hsp90 inhibitor

Novel microtubule polymerization inhibitor with little susceptible to transporter-mediated chemoresistance

Novel Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitor