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Lenalidomide-CO-C7-NH2

  Cat. No.:  DC80953  
Chemical Structure
193903-41-2
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More than 5000 active chemicals with high quality for research!
Field of application
Lenalidomide-CO-C7-NH2 is a CRBN-dependent intermediate of BET PROTAC degrader. Consisting of the E3 ubiquitin ligase ligand Lenalidomide conjugated with a PROTAC linker, Lenalidomide-CO-C7-NH2 induces the specific degradation of the oncoprotein BRD4. By depleting BRD4, Lenalidomide-CO-C7-NH2 effectively inhibits cancer cell proliferation, induces cell cycle arrest and promotes apoptosis, thereby exhibiting significant anti-tumor activity in xenograft models. Lenalidomide-CO-C7-NH2 serves as an important tool molecule for the study of acute myeloid leukemia.
Cas No.: 193903-41-2
Chemical Name: Lenalidomide-CO-C7-NH2
Formula: C12H21NO4
M.Wt: 243.3
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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