17-GMB-APA-GA|CAS 256337-10-7|DC Chemicals

Cas No.:	256337-10-7
Chemical Name:	17-GMB-APA-GA
SMILES:	O=C(N1CCCC(NCCCNC2=C(C3=O)C[C@H](C[C@@H]([C@@H]([C@@H](C)/C=C(C)/[C@@H]([C@@H](OC)/C=C\C=C(C)\C(NC3=CC2=O)=O)OC(N)=O)O)OC)C)=O)C=CC1=O
Formula:	C₃₉H₅₃N₅O₁₁
M.Wt:	767.87
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Cat. No.	Product name	Field of application
DC46953	Icapamespib	Icapamespib (PU-HZ151) is a potent HSP90 inhibitor with an EC50 of 5 nM. Icapamespib is able to cross blood-brain barrier.
DC45687	HA15-Biotin	HA15-Biotin is a chemical probe that consists of HA15 and biotin attached on the amide part of HA15. HA15-Biotin exhibits similar levels of activity to HA15. HA15-Biotin can be used for proteomic analysis.
DC44918	Aminohexylgeldanamycin hydrochloride	Aminohexylgeldanamycin (AHGDM) hydrochloride, a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin hydrochloride shows antiangiogenic and antitumor activities.
DC41386	10,11-Dehydrocurvularin	10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity.
DC41299	Eupalinolide A	Eupalinolide A, isolated from Eupatorium lindleyanum, induces the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90.
DC40719	Geldanamycin-FITC	Geldanamycin-FITC, a Geldanamycin fluorescent probe, can be used in a fluorescence polarization assay for HSP90 inhibitors. Geldanamycin-FITC also can be used for detection of cell surface HSP90.
DC40630	Aminohexylgeldanamycin	Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities.
DC40629	17-AEP-GA	17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin.
DC40452	17-GMB-APA-GA	17-GMB-APA-GA is an ADC Cytotoxin. 17-GMB-APA-GA is a potent HSP90 inhibitor and used for latent T. gondii infection research.
DC40066	Arimoclomol citrate	Arimoclomol citrate (BRX-220 citrate) is a co-inducer of heat shock proteins (HSP). Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.