8-Bromo-cAMP|cas 76939-46-3|DC Chemicals

Cas No.:	76939-46-3
Chemical Name:	8-Bromo-cAMP
Synonyms:	Adenosine, 8-bromo-,cyclic 3',5'-(hydrogen phosphate), monosodium salt (9CI);8-BR-CAMP NA;8-BroMoadenosine 3',5'-cyclic Monophosphate sodiuM salt;8-Bromo-cAMP, sodium salt;8-Bromo-cAMP, sodium salt,8-Bromoadenosine-3',5'-cyclicmonophosphatesodiumsalt;8-bromo-Cyclic AMP (sodium salt);8-BR-CAMP SODIUM SALT;8-BROM-ADENOSIN-3',5'-CYCLOPHOSPHAT;8-Bromoadenosine 3',5'-phosphoric acid sodium salt;8-bromoadenosine 3:5-cyclic*monophosphate sodiu;8-BROMOADENOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM;8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT;8-BROMO-CAMP,NA;CAMP,8-BR,NA;8-Br-cAMP;4H-Furo[3,2-d]-1,3,2-dioxaphosphorin,adenosine deriv.;8-Bromo-cAMP sodium salt;1PVH7X89H4;8-bromo-cAMP;MLS002153216;SMR000326869;8-Bromo-cAMP(sodium salt);MLS000860010;8-Bromo cyclic AMP sodium salt;AOB5956;HMS2233B10;HMS3412M07;B9000;8-Bromo-adenosine 3',5'-cyclic-monophosphate, sodi
SMILES:	BrC1=NC2=C(N([H])[H])N=C([H])N=C2N1[C@@]1([H])[C@@]([H])([C@@]2([H])[C@@]([H])(C([H])([H])OP(=O)([O-])O2)O1)O[H].[Na+]
Formula:	C₁₀H₁₀BrN₅NaO₆P
M.Wt:	430.0838
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA)[1].

In Vitro:

8-Bromo-cAMP sodium salt is a brominated derivative of cyclic AMP. 8-Bromo-cAMP sodium salt enhances the efficiency of cellular reprogramming. 8-Bromo-cAMP sodium salt improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. 8-Bromo-cAMP sodium salt inhibits proliferation, induce differentiation and apoptosis in a malignant glioma cell line (A-172) and an esophageal cancer cell line (Eca-109)[1].

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