[Ala17]-MCH|CAS 359784-84-2|DC Chemicals

Cas No.:	359784-84-2
Chemical Name:	[ala17]-mch
Synonyms:	[ala17]-mch;BU 239 hydrochloride;
SMILES:	CSCC[C@@H]1NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(=O)O)N)=O)CC2C=CC=CC=2)=O)CC(=O)O)=O)CCSC)=O)CC(C)C)=O)CCCNC(=N)N)=O)CSSC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)O)C(C)C)=O)CCC(=O)N)=O)C)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CC(C)C)NC1=O
Formula:	C₉₇H₁₅₅N₂₉O₂₆S₄
M.Wt:	2271.7073
Purity:	>98%
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Cat. No.	Product name	Field of application
DC43987	MCHR1 antagonist 2	MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells.
DC41656	[Ala17]-MCH TFA	[Ala17]-MCH TFA, a MCH analogue, is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM). [Eu3+ chelate-labeled [Ala17]-MCH shows high affnity for MCHR1 (Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2.
DC41655	[Ala17]-MCH	[Ala17]-MCH, a MCH analogue, is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM). [Eu3+ chelate-labeled [Ala17]-MCH shows high affnity for MCHR1 (Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2.
DC28204	SNAP 94847 hydrochloride	SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters.