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Bafetinib (INNO-406)

Cat. No.: DC2013 Featured

Chemical Structure

859212-16-1

For research use only. We do not sell to patients.

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Field of application

Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM and 19 nM, respectively.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	859212-16-1
Chemical Name:	(S)-4-((3-(dimethylamino)pyrrolidin-1-yl)methyl)-N-(4-methyl-3-(4-(pyrimidin-5-yl)pyrimidin-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide
Synonyms:	NS-187, Bafetinib, INNO406
SMILES:	O=C(C1=CC=C(C(C(F)(F)F)=C1)CN2C[C@@H](N(C)C)CC2)NC3=CC=C(C)C(NC4=NC=CC(C5=CN=CN=C5)=N4)=C3
Formula:	C₃₀H₃₁F₃N₈O
M.Wt:	576.62
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Bafetinib is a Lyn and Bcr-Abl tyrosine kinase inhibitor with potential antineoplastic activity.

Cat. No.	Product name	Field of application
DC3144	Nilotinib	Nilotinib (AMN-107, Tasigna) is a Bcr-Abl inhibitor with IC50 less than 30 nM.
DC2013	Bafetinib (INNO-406)	Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM and 19 nM, respectively.

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