CBR-470-1|CAS 2416095-06-0|DC Chemicals

Cas No.:	2416095-06-0
Chemical Name:	Schembl21033073
Synonyms:	(3R,4S)-3-((4-Chlorophenyl)sulfonyl)-4-(isobutylamino)tetrahydrothiophene 1,1-dioxide;rel-(3R,4S)-3-((4-Chlorophenyl)sulfonyl)-4-(isobutylamino)tetrahydrothiophene 1,1-dioxide;(3R,4S)-3-[(4-chlorophenyl)sulfonyl]-4-(isobutylamino)tetrahydro-1H-1lambda-thiophene-1,1-dione;Schembl21033073;CBR-470-1
SMILES:	ClC1C([H])=C([H])C(=C([H])C=1[H])S([C@@]1([H])C([H])([H])S(C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])(=O)=O)(=O)=O
Formula:	C₁₄H₂₀ClNO₄S₂
M.Wt:	365.8959
Purity:	>98%
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Description:

CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade.

Cat. No.	Product name	Field of application
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DC40756	CBR-470-1	CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade.
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