CRAC intermediate 2|CAS 123066-64-8|DC Chemicals

Cas No.:	123066-64-8
Chemical Name:	CRAC intermediate 2
SMILES:	NC1=CC=C(N2N=C(C(F)(F)F)C=C2C(F)(F)F)C=C1
Formula:	C₁₁H₇F₆N₃
M.Wt:	295.18
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC76747	CRAC intermediate 2	CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis, extracted from patent WO 2013059666A1.
DC71364	5J-4	5J-4 is a potent CRAC inhibitor. 5J-4 decreases the numbers of infiltrated mononuclear cell into the CNS, and significantly decreases the population of infiltrated CD4+ population. 5J-4 reduces the symptoms and delayed the onset of EAE (experimental autoimmune encephalomyelitis) in mouse model of inflammation.
DC71363	piCRAC-1	piCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage.
DC70467	GSK-5498A	GSK-5498A is a potent, selective small molecule blocker of Calcium-Release Activated Calcium (CRAC) channel with IC50 of 1 uM; completely inhibits calcium influx through CRAC channels, inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells from multiple human and rat preparations.