Compound 3-110-22|

Cas No.:
Chemical Name:	(E)-2-(benzofuran-2-yl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetohydrazonoyl cyanide
SMILES:	C(=N/NC1=CC=CC(C(F)(F)F)=C1)(/C#N)\C(C1=CC2=CC=CC=C2O1)=O
Formula:	C₁₈H₁₀F₃N₃O₂
M.Wt:	357.292
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Compound 3-110-22 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E; inhibits ZIKV PF13-251013-18 with IC90 of 4.0 uM, interacts with recombinant, soluble ZIKV E (ZIKV sE) in biolayer interferometry experiments with a KD of 2.1 uM; inhibits other flavivirus pathogens, inhibits DENV fusion by targeting E; also inhibits West Nile reporter virus with IC50 of 2.9 uM.

Cat. No.	Product name	Field of application
DC44908	2'-Deoxy-5'-O-DMT-2'-fluorouridine	2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.
DC10934	JBJ-16-111	JBJ-16-111 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E..
DC10933	Compound 3-110-22	Compound 3-110-22 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E.