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| Cas No.: | |
| Chemical Name: | 2-(2-(methylamino)pyrimidin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one |
| Synonyms: | FOXO1 inhibitor 8 |
| SMILES: | C(=O)1NCCC2NC(C3C=CN=C(NC)N=3)=CC1=2 |
| Formula: | C12H13N5O |
| M.Wt: | 243.27 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A small molecule, selective FOXO1 inhibitor that inhibits FOXO-dependent glucose production devoid of lipogenic activity in hepatocytes; shows beneficial effects of FOXO1 inhibition on diabetic hyperglycemia by reducing hepatic glucose production. |