Quilseconazole|VT-1129;VT1129

Cas No.:	1340593-70-5
Chemical Name:	Quilseconazole
Synonyms:	Quilseconazole
SMILES:	FC(C1C([H])=C([H])C(C2C([H])=C([H])C(=C([H])C=2[H])OC(F)(F)F)=C([H])N=1)([C@](C1C([H])=C([H])C(=C([H])C=1F)F)(C([H])([H])N1C([H])=NN=N1)O[H])F
Formula:	C₂₂H₁₄F₇N₅O₂
M.Wt:	513.3677
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A novel selective, orally available fungal CYP51 (lanosterol 14-α-demethylase) inhibitor; displays greater selectivity for fungal enzyme than for mammalian CYP450 compared to the approved azole class of antifungal drugs; inhibits C. albicans and T. rubrum with MIC of <0.001 ug/mL, also demonstrated potent activities against Cryptococcusspecies as demonstrated by low MIC50 and MIC90 values.

Cat. No.	Product name	Field of application
DCAPI1093	Posaconazole	Posaconazole (Noxafil) is a sterol C14ɑ demethylase inhibitor with an IC50 of 0.25 nM.
DCAPI1497	Cancidas	Caspofungin is a semi-synthetic analogue of pneumocandin B0 with improved water solubility, a significant limitation in the development of the echinocandin class as pharmaceuticals. Caspofungin acts by inhibition of the synthesis of β (1,3)-D-glucan, an e
DC11527	Quilseconazole	A novel selective, orally available fungal CYP51 (lanosterol 14-α-demethylase) inhibitor.