JNJ-2408068|RSV inhibitor|DC Chemicals

Cas No.:	317846-22-3
Chemical Name:	2[[2-[[1-(2-aminoethyl)-4-piperidinyl]amino]-4-methyl-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol
Synonyms:	R-170591;R170591;JNJ 2408068;JNJ2408068
SMILES:	C(CN1C(NC2CCN(CCN)CC2)=NC2=C(C)C=CC=C21)1=NC(C)=CC=C1O
Formula:	C₂₂H₃₀N₆O
M.Wt:	394.523
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Wyde PR, et al. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov;60(3):221-31.

Description:	JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].
Target:	RSV-A RSV-B
References:	[1]. Wyde PR, et al. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov;60(3):221-31.

Cat. No.	Product name	Field of application
DC11647	JNJ-2408068	JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].