YM-53403|YM 53403;YM53403

Cas No.:	851331-05-0
Chemical Name:	6-(4-([1,1'-biphenyl]-2-carboxamido)benzoyl)-N-cyclopropyl-5,6-dihydro-4H-benzo[b]thieno[2,3-d]azepine-2-carboxamide
Synonyms:	YM 53403;YM53403
SMILES:	N(C(=O)C1=CC=C(NC(C2=CC=CC=C2C2=CC=CC=C2)=O)C=C1)1CCC2C=C(C(NC3CC3)=O)SC=2C2=CC=CC=C12
Formula:	C₃₆H₂₉N₃O₃S
M.Wt:	583.706
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays; displays 100-fold more potent than ribavirin, an attractive compound for the treatment of RSV infection.

Cat. No.	Product name	Field of application
DC47013	(S)-Enzaplatovir	(S)-Enzaplatovir ((S)-BTA-C585) is the S-enantiomer of Enzaplatovir. (S)-Enzaplatovir shows antiviral activities with an EC50 of 56 nM for respiratory syncytial viral (RSV) (patent WO2011094823A1 compound 77).
DC41364	ent-11β-Hydroxyatis-16-ene-3,14-dione	ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots of Euphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione has anti-RSV activity.
DC40330	Quercetin pentaacetate	Quercetin pentaacetate could interact with F-protein with lower binding energy and better stability to block viral adhesion. Quercetin pentaacetate interacts with RSV and inhibit the viral adhesion on cell surface.
DC9618	TMC353121	TMC353121 is a potent RSV fusion inhibitor with pEC50 of 9.9(t1/2 in lung = 25 h).
DC10435	RSV604 racemate	RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer.
DC11774	YM-53403	A specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays.
DC11773	BI Compound D	A potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM.
DC11771	AZ-27	A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively.