V-9302|V9302|cas 1855871-76-9

Cas No.:	1855871-76-9
Chemical Name:	(S)-2-Amino-4-(bis(2-((3-methylbenzyl)oxy)benzyl)amino)butanoic acid
Synonyms:	V-9302; V9302; V 9302
SMILES:	O=C(O)[C@@H](N)CCN(CC1=CC=CC=C1OCC2=CC=CC(C)=C2)CC3=CC=CC=C3OCC4=CC=CC(C)=C4
Formula:	C₃₄H₃₈N₂O₄
M.Wt:	538.28
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	V-9302 is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 with an IC50 of 9.6 μM. V-9302 exhibits anti-tumor activity[1].
Target:	IC50: 9.6 μM (ASCT2)[1]
References:	[1]. Schulte ML, et al. Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacyin preclinical models. Nat Med. 2018 Feb;24(2):194-202.

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