E3 ligase Ligand 1A|cas 1948273-02-6|DC Chemicals

Cas No.:	1948273-02-6
Chemical Name:	VHL ligand 2;(S,R,S)-AHPC-Me
Synonyms:	VHL ligand 2;(S,R,S)-AHPC-Me
SMILES:	N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O
Formula:	C₂₇H₂₈N₂O₅S₂
M.Wt:	444.59
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9.

Description:

E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer.

Cat. No.	Product name	Field of application
DC22337	E3 ligase Ligand 4(TC-E3 5032)	E3 ligase Ligand 4 is a ligand of E3 ligase, used in PROTAC technology.
DC20512	VHL ligand 1	PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation..
DC22335	E3 ligase Ligand 1A	E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer. (S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL)