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Y 39983HCl

  Cat. No.:  DC60182   Featured
Chemical Structure
471843-75-1
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More than 5000 active chemicals with high quality for research!
Field of application
Y-39983, also known as Y-33075, is a potent and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK. Y-39983 attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination. Y-39983 downregulates RhoA/Rho-associated kinase expression during its promotion of axonal regeneration. Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats.
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 471843-75-1
Chemical Name: Y-39983 HCl
Synonyms: Y 39983;4-[(1R)-1-aminoethyl]-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide,hydrochloride;(R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide 1 hydrochloride;(R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide hydrochloride;(R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide monohydrochloride;Benzam;hydrochloric acid salt of (R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide;KB-81513;KB-81517;SureCN1927760;UNII-3304VH0J6B;Y 39983,hydrochloride;Y-39983;Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1);3304VH0J6B;4-[(1R)-1-aminoethyl]-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide;hydrochloride;Y 39983HCl;4-[(1R)-1-Aminoethyl]-N-1H-pyrrolo[2,3-b]pyridin-4-ylbenzamide hydrochloride;A937203;Q27256201;4-((1r)-1-aminoethyl)-n-1h-pyrrolo[2,3-b]pyridin-4-ylbenzamide hcl;(R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benz;Y 39983, (HCl);(594859-54-8) y 39983;4-[(1R)-1-Aminoethyl]-N-1H-pyrrolo[2,3-b]pyridin-4-ylbenzamide hydrochloride ISO 9001：2015 REACH;Y-39983 HCI
SMILES: Cl[H].O=C(C1C([H])=C([H])C(=C([H])C=1[H])[C@@]([H])(C([H])([H])[H])N([H])[H])N([H])C1C([H])=C([H])N=C2C=1C([H])=C([H])N2[H]
Formula: C16H17ClN4O
M.Wt: 316.789
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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