Camibirstat (FHD-286)|CAS 2671128-05-3|DC Chemicals

Cas No.:	2671128-05-3
Chemical Name:	FHD-286
Synonyms:	N-[(S)-1-[[4-[6-(cis-2,6-Dimethylmorpholino)pyridin-2-yl]thiazol-2-yl]amino]-3-methoxy-1-oxopropan-2-yl]-1-(methylsulfonyl)-1H-pyrrole-3-carboxamide;FHD-286;SMARCA4/SMARCA2 ATPase Inhibitor FHD-286;1H-Pyrrole-3-carboxamide, N-((1S)-2-((4-(6-((2R,6S)-2,6-dimethyl-4-morpholinyl)-2-pyridinyl)-2-thiazolyl)amino)-1-(methoxymethyl)-2-oxoethyl)-1-(methylsulfonyl)-;GTPL11967;F78342;AKOS040759962;N-[(2S)-1-[[4-[6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]pyridin-2-yl]-1,3-thiazol-2-yl]amino]-3-methoxy-1-oxopropan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide;HY-144835;N-((S)-1-(4-(6-((2S,6R)-2,6-dimethylmorpholino)pyridin-2-yl)thiazol-2-ylamino)-3-methoxy-1-oxopropan-2-yl)-1-(methylsulfonyl)-1H-pyrrole-3-carboxamide;FHD286;QHA5XLA4SA;camibirstat [INN];Camibirstat;NSC-840947;MS-30210;N-[(1S)-2-[[4-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-1-(methoxymethyl)-2-oxoethyl]-1-(methylsulfonyl)-1H-pyrrole-3-carboxamide;CHEMBL5095181;2671128-05-3;FHD-286?;UNII-QHA5XLA4SA;1H-Pyrrole-3-carboxamide, N-[(1S)-2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-1-(methoxymethyl)-2-oxoethyl]-1-(methylsulfonyl)-;BRG1/BRM Inhibitor FHD-286;N-((2S)-1-((4-(6-((2S,6R)-2,6-dimethylmorpholin-4-yl)pyridin-2-yl)-1,3-thiazol-2-yl)amino)-3-methoxy-1-oxopropan-2-yl)-1-methylsulfonylpyrrole-3-carboxamide;NSC840947;EX-A6082;CS-0435579;FHD 286;SCHEMBL23673174;N-[(2S)-1-[[4-[6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-2-yl]-1,3-thiazol-2-yl]amino]-3-methoxy-1-oxopropan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide
SMILES:	[C@H]1(C)O[C@@H](C)CN(C2=NC(C3N=C(NC(=O)[C@@H](NC(=O)C4=CN(S(=O)(C)=O)C=C4)COC)SC=3)=CC=C2)C1
Formula:	C₂₄H₃₀N₆O₆S₂
M.Wt:	562.66
Purity:	>98%
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.
Publication:	[1]. Centore, Richard C. et al. Preparation of BRG1/BRM inhibitors for treating cancer. US20220079940 A1.

Description:

FHD-286 is a BRG1/BRM ATPase inhibitor for the treatment of BAF-related disorders such as acute myeloid leukemia.

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