APOL1-IN-1|cas 2446817-72-5|DC Chemicals

Cas No.:	2446817-72-5
Chemical Name:	APOL1-IN-1
Synonyms:	1H-Indole-3-propanamide, 2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-
SMILES:	[C@H]1(CNC(=O)[C@H]1NC(=O)CCC1C2=C(NC=1C1=CC=C(C=C1)F)C=CC=C2)O
Formula:	C₂₁H₂₀FN₃O₃
M.Wt:	381.40
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD)[1].
Target:	Apolipoprotein LI (APOL1)[1]
References:	[1]. Brodney M, et, al. Inhibitors of apol1 and methods of using same. WO2020131807A1.

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