Sigma-1 receptor antagonist 2|CAS 1639220-15-7|DC Chemicals

Cas No.:	1639220-15-7
Chemical Name:	sigma-1 Receptor antagonist 2
Synonyms:	BDBM50034160;5-Chloro-2-(4-methoxyphenyl)-4-methyl-6-(3-(piperidin-1-yl)propoxy)pyrimidine
SMILES:	ClC1=C(C([H])([H])[H])N=C(C2C([H])=C([H])C(=C([H])C=2[H])OC([H])([H])[H])N=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
Formula:	C₂₀H₂₆ClN₃O₂
M.Wt:	375.8923
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively[1].
Target:	Ki: 3.88 nM (σ1 receptor), 1288 nM (σ2 receptor)[1]
References:	[1]. Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.

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sigma-1 Receptor antagonist 2