DGY-06-116|CAS 2556836-50-9|DC Chemicals

Cas No.:	2556836-50-9
Chemical Name:	4-((2-acrylamidophenyl)amino)-N-(2-chloro-6-methylphenyl)-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide
Synonyms:	DGY-06-116; DGY 06 116; DGY 06-116; DGY-06 116
SMILES:	O=C(C1=C(N=C(NC2C=CC(N3CCN(C)CC3)=CC=2)N=C1)NC1C=CC=CC=1NC(=O)C=C)NC1C(C)=CC=CC=1Cl
Formula:	C₃₂H₃₃ClN₈O₂
M.Wt:	597.11
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	1: Du G, Rao S, Gurbani D, et al. Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine. J Med Chem. 2020;63(4):1624-1641. doi:10.1021/acs.jmedchem.9b01502 2: Gurbani D, Du G, Henning NJ, et al. Structure and Characterization of a Covalent Inhibitor of Src Kinase. Front Mol Biosci. 2020;7:81. Published 2020 May 19. doi:10.3389/fmolb.2020.00081

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