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DMHAPC-Chol

  Cat. No.:  DC36459   Featured
Chemical Structure
794494-38-5
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More than 5000 active chemicals with high quality for research!
Field of application
DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells. DMHAPC-Chol, as part of a lipoplex with DOPE, has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF.
Cas No.: 794494-38-5
Chemical Name: DMHAPC-Chol
Synonyms: DMHAPC Chol, Dimethyl Hydroxyethyl Aminopropane Carbamoyl Cholesterol Iodide
SMILES: C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(NCCC[N+](C)(C)CCO)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Formula: C35H63N2O3
M.Wt: 559.9
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC45677 5α-Cholesta-7,24-dien-3β-ol 5α-Cholesta-7,24-dien-3β-ol, a sterol, can be found in hamster cauda epididymal mature spermatozoa.
DC36834 Sitostanol Sitostanol is a saturated sterol found in a variety of plants, including corn, wheat, and rice and reduces cholesterol uptake in rats and rabbits.
DC36459 DMHAPC-Chol DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells. DMHAPC-Chol, as part of a lipoplex with DOPE, has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF.
DC32956 Desmosterol Desmosterol is an endogenous agonist of RORgamma; Intermediate in the synthesis of cholesterol.
DC12188 Lathosterol Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis.
DC12199 Cholestenone Cholestenone is the intermediate oxidation product of cholesterol.
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