Defensamide(MHP)|cas 1104874-94-3|DC Chemicals

Cas No.:	1104874-94-3
Chemical Name:	N-Hexanoyltyrosine methyl ester
Synonyms:	MHP;Defensamide;N-Hexanoyltyrosine methyl ester;8GJP2KSJ0T;(S)-Methyl 2-(hexanamido)-3-(4-hydroxyphenyl)propanoate;Defensamide(MHP);methyl caprooyl tyrosinate;L-Tyrosine, N-(1-oxohexyl)-, methyl ester;methyl (2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoate;BCP29060;s6512;ZB1539;Q27270419;(S)-methyl 2-hexanamido-3-(4-hydroxyphenyl)propanoate
SMILES:	O(C([H])([H])[H])C([C@]([H])(C([H])([H])C1C([H])=C([H])C(=C([H])C=1[H])O[H])N([H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)=O
Formula:	C₁₆H₂₃NO₄
M.Wt:	293.3581
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	MHP is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.
References:	[1]. Jeong SK, et al. Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. J Dermatol Sci. 2015 Sep;79(3):229-34.

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