Drospirenone|cas 67392-87-4|DC Chemicals

Cas No.:	67392-87-4
Chemical Name:	Drospirenone
Synonyms:	Drospirenone;6b,7b;15b,16b-dimethylen-3-oxo-17a-pregn-4-ene-21,17-carbolactone;dihydrospirorenone;6-methyleneandrost-4-ene-3,17-dione;Drospireone;DROSPIREONE F·S;arbolactone;Dorospirenone;Drospirenon;Drospirenona;ZK 3059;6b,7b:15b,16b-Dimethylen-3-oxo-17a-pregn-4-ene-21,17-carbolactone;Dehydrospirorenone;Drospirenonum;1,2-Dihydrospirorenone;DRSP;Drospirenonum [INN-Latin];Drospirenona [INN-Spanish];ZK 30595;ZK30595;C24H30O3;N295J34A25;DSSTox_RID_81639;DSSTox_CID_2646
SMILES:	O1C(C([H])([H])C([H])([H])[C@@]21[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])C(C([H])=C4[C@]4([H])C([H])([H])[C@]4([H])[C@@]3([H])[C@]1([H])[C@]1([H])C([H])([H])[C@@]12[H])=O)=O
Formula:	C₂₄H₃₀O₃
M.Wt:	366.4932
Purity:	>99%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Drospirenone(Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone.

References:

[1]. Fuhrmann, U., et al., The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential. Contraception, 1996. 54(4): p. 243-51. [2]. Muhn, P., et al., Drospirenone: a novel progestogen with antimineralocorticoid and antiandrogenic activity. Pharmacological characterization in animal models. Contraception, 1995. 51(2): p. 99-110. [3]. Warming, L., et al., Safety and efficacy of drospirenone used in a continuous combination with 17beta-estradiol for prevention of postmenopausal osteoporosis. Climacteric, 2004. 7(1): p. 103-11.

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