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EST73502 HCl

  Cat. No.:  DC39710   Featured
Chemical Structure
2307458-82-6
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More than 5000 active chemicals with high quality for research!
Field of application
EST73502 is a dual μ-opioid receptor agonist and σ1 receptor antagonist with Ki of 64 nM and 118 nM, respectively.
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 2307458-82-6
Chemical Name: (R)-9-(2,5-difluorophenethyl)-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Synonyms: EST73502; EST 73502; EST-73502
SMILES: O=C1[C@@H](C)OC2(CCN(CCC3C(F)=CC=C(F)C=3)CC2)CN1CC.Cl
Formula: C19H27ClF2N2O2
M.Wt: 388.88
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ 1 Receptor Antagonist Clinical Candidate for the Treatment of Pain--J Med Chem . 2020 Oct 16. doi: 10.1021/acs.jmedchem.0c01127
Description: EST73502 is a dual μ-opioid receptor agonist and σ1 receptor antagonist with Ki of 64 nM and 118 nM, respectively.
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