Galanthamine hydrobromide|cas 1953-04-4|DC Chemicals

Cas No.:	1953-04-4
SMILES:	Br.COC1=CC=C2C3[C@@]4(C=C[C@H](O)C[C@H]4OC1=3)CCN(C2)C
Formula:	C₁₇H₂₂BrNO₃
M.Wt:	368.27
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase(AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors.Galanthamine hydrobromide prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. Long-term administration reduces amyloid precursor protein deposition and neurodegeneration in a mouse model of Alzheimer's disease.

Cat. No.	Product name	Field of application
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DCAPI1543	Neostigmine Methylsulfate	Neostigmine Methyl Sulfate is a reversible acetylcholinesterase inhibitor. This compound blocks the breakdown of acetylcholine in the synaptic space, leading to prolonged signaling and thus increased muscle contractions.
DC9046	Neostigmine bromide	Neostigmine Bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis.
DCAPI1460	Naratriptan hydrochloride	Naratriptan Hydrochloride is a triptan drug which is used for the treatment of migraine headaches.
DC9090	Galanthamine hydrobromide	Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase(AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors.
DC9102	Donepezil	Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.