IDE-2（ESCs inducer）|CAS 1136466-93-7|DC Chemicals

Cas No.:	1136466-93-7
Chemical Name:	7-(2-cyclopentylidenehydrazino)-7-oxoheptanoic Acid
SMILES:	OC(=O)CCCCCC(=O)NN=C1CCCC1
Purity:	>98%
Sotrage:	4°C for 1 year, -20°C for more than 2 years

Description:

IDE-2 is a cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 223 nM for induction of Sox17 expression in ESCs). Reported to activate TGF-β signaling and downstream Smad2 phosphorylation; upregulates Nodal expression. Promotes pancreatic progenitor cell formation in vitro, and gut tube formation in vivo.

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