Imiquimod|cas 99011-02-6|DC Chemicals

Cas No.:	99011-02-6
SMILES:	CC(CN1C=NC2C(=NC3C=CC=CC=3C1=2)N)C
Formula:	C₁₄H₁₆N₄
M.Wt:	240.3
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Imiquimod is an immune response modifier and a toll-like receptor 7 agonist.

In Vivo:

In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1].

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