KHS-101|cas 1262770-73-9|DC Chemicals

Cas No.:	1262770-73-9
Chemical Name:	KHS-101 free base
Synonyms:	N4-isobutyl-N2-((2-phenylthiazol-4-yl)Methyl)pyriMidine-2,4-diaMine;N4-isobutyl-N2-[(2-phenylthiazol-4-yl)methyl]pyrimidine-2,4-diami ne
SMILES:	CC(C)CN=C1C=CN=C(NCC2=CSC(=N2)C3=CC=CC=C3)N1
Formula:	C₁₈H₂₁N₅S
M.Wt:	339.461
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Selective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM). Suppresses astrocyte formation. Also induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo.

Cat. No.	Product name	Field of application
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DC8390	Oltipraz	Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3.
DC12043	KHS-101	KHS101 is a selective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM).
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