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Mutant IDH1-IN-4

Cat. No.: DC28343

Chemical Structure

1416270-18-2

For research use only. We do not sell to patients.

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Field of application

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1416270-18-2
Formula:	C₂₅H₃₄N₄O₃
M.Wt:	438.56
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC46300	IDH-C227	IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts.
DC45831	WT IDH1 Inhibitor 2	WT IDH1 Inhibitor 2 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor with an IC50 value of 120 nM. WT IDH1 Inhibitor 2 as a mutant R132H IDH1 inhibitor, is an isomer of GSK321 with some wild-type cross reactivity.
DC28343	Mutant IDH1-IN-4	Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.