NCGC00092410|CAS 442898-34-2|DC Chemicals

Cas No.:	442898-34-2
Chemical Name:	NCGC00092410
SMILES:	O=C(C1CCCCC1)NC2=CC=C3N=C(N4CCOCC4)C=C(C)C3=C2
Formula:	C₂₁H₂₇N₃O₂
M.Wt:	353.46
Purity:	>98%
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Description:

NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC), with an IC50 of 31 nM. NCGC00092410 shows no activity against the related hydrolases at concentrations up to 77 μM. NCGC00092410 is a GC chaperone and increases the activity and lysosomal localization of glucocerebrosidase in mutant cell lines. NCGC00092410 can be used for the research of Gaucher disease.

Cat. No.	Product name	Field of application
DC42342	NCGC00092410	NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC), with an IC50 of 31 nM. NCGC00092410 shows no activity against the related hydrolases at concentrations up to 77 μM. NCGC00092410 is a GC chaperone and increases the activity and lysosomal localization of glucocerebrosidase in mutant cell lines. NCGC00092410 can be used for the research of Gaucher disease.