PARGYLINE HYDROCHLORIDE|cas 306-07-0

Cas No.:	306-07-0
Synonyms:	NSC 43798
SMILES:	CN(CC#C)CC1=CC=CC=C1.Cl
Formula:	C₁₁H₁₄ClN
M.Wt:	195.69
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension.

References:

[1]. Bianchi P, et al. A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. FASEB J. 2005 Apr;19(6):641-3. [2]. Fuentes JA, et al. Central mediation of the antihypertensive effect of pargyline in spontaneously hypertensive rats. Eur J Pharmacol. 1979 Jul 15;57(1):21-7. [3]. Puig M, et al. Effect on the sympathetic nervous system of chronic treatment with pargyline and l-Dopa. J Pharmacol Exp Ther. 1972 Jul;182(1):130-4.

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