PBIT|JHDM Innhibits|CAS 2514-30-9

Cas No.:	2514-30-9
Chemical Name:	Jumonji HDM Inhibitor
Synonyms:	Jumonji HDM Inhibitor
SMILES:	S1C2=C(C=CC=C2)C(=O)N1C1=CC=C(C)C=C1
Formula:	C₁₄H₁₁NOs
M.Wt:	241.31
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1(JARID1) enzymes. PBIT inhibits JARID1B (KDM5B or PLU1 ) histone demethylase an IC50 of about 3 μM . PBIT also inhibits JARID1A and JARID1C with IC5 s of 6 and 4.9 μM, respectively[1].

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