PD-1-IN-17|cas 1673560-66-1|DC Chemicals

Cas No.:	1673560-66-1
Chemical Name:	CA-170 free base
Synonyms:	CA-170; CA-170; CA-170; AUPM 170; AUPM-170; AUPM170; PD-1-IN-1
SMILES:	OC[C@@H](C(O)=O)NC(N[C@H](C1=NN=C([C@@H](N)[C@H](O)C)O1)CCC(N)=O)=O
Formula:	C₁₃H₂₂N₆O₇
M.Wt:	374.354
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	PD-1-IN-17 is a programmed cell death- 1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM[1].
Target:	PD-1[1]
References:	[1]. Pottayil Govindan Nair Sasikumar, et al. 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators. WO2015033301A1

Cat. No.	Product name	Field of application
DC8381	PD-1/PD-L1 inhibitor 2(BMS-202)	PD-1/PD-L1 inhibitor 2 is reported to prevent the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM,a useful compound immunomodulator compound.
DC9280	BMS-1 (PD1/PDL1 inhibitor 1)	PD-1/PD-L1 inhibitor 1 is a PD-1/PD-L1 interaction inhibitor,IC50 values: 0.006-0.10 μM,a useful immunomodulator compound.
DC10330	PD-1-IN-17(CA-170)	CA-170, also known as AUPM170 and PD-1-IN-17, is a programmed cell death-1 (PD-1) inhibitor. PD-1-IN-17 was first reported in patent WO2015033301A1, (Compound 4), inhibits 92% splenocyte proliferation at 100 nM.

PD-1-IN-17(CA-170)