PKC-theta inhibitor|CAS 736048-65-0

Cas No.:	736048-65-0
SMILES:	FC(F)(F)OC1=CC=CC=C1CNC2=NC=C([N+]([O-])=O)C(NCC3CCC(CN)CC3)=N2
Formula:	C₂₀H₂₅F₃N₆O₃
M.Wt:	454.45
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO

Description:	PKC-theta inhibitor is a selective PKC-θinhibitor, with an IC50 of 12 nM.
Target:	PKCθ:12 nM (IC50)
References:	[1]. Cywin CL, et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1;17(1):225-30.

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