PRE-084(PRE084)|Sigma-1 inhibitor|DC Chemicals

Cas No.:	138847-85-5
Chemical Name:	Cyclohexanecarboxylic acid, 1-phenyl-, 2-(4-morpholinyl)ethyl ester hydrochloride
Synonyms:	PRE 084; PRE-084; PRE084. PRE-084 HCl; PRE-084 hydrochloride
SMILES:	O=C(C1(C2=CC=CC=C2)CCCCC1)OCCN3CCOCC3.[H]Cl
Formula:	C₁₉H₂₈ClNO₃
M.Wt:	353.887
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

PRE-084 hydrochloride is a high affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively).

Cat. No.	Product name	Field of application
DC9264	S1RA hydrochloride	S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM).
DC7274	S1RA	S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM).
DC8347	PRE-084 hydrochloride	PRE-084 hydrochloride is a high affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively).
DC10455	NE-100	NE100 hydrochloride is a potent and selective σ1 receptor antagonist (Ki = 0.86 nM) that displays > 55-fold selectivity over σ2 receptors and > 6000-fold selectivity over D1,
DC10280	BD1063 dhydrochloride	BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist.
DC8313	BD1047.2HBr	BD 1047 dihydrobromide is a selective antagonist of σ receptors.