PT2977|MK-6482|HIF-2α inhibitor|DC Chemicals

Cas No.:	1672668-24-4
Synonyms:	PT2977,MK-6482,PT2977,PT2977,MK 6482,MK6482
SMILES:	N#CC1C=C(OC2C3[C@H]([C@H]([C@@H](O)C=3C(S(=O)(C)=O)=CC=2)F)F)C=C(F)C=1
Formula:	C₁₇H₁₂F₃NO₄S
M.Wt:	383.34
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Xu R, et al. 3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma. J Med Chem. 2019 Aug 8;62(15):6876-6893.

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